Bristol Myers Squibb Scientist I, Protein Engineering (1) in Redwood City, California

Scientist I, Protein Engineering

Job Description:

We are seeking a skilled and enthusiastic Protein/Antibody engineer to join the Protein Engineering Group. The candidate will be expected to work on a variety of protein engineering projects to optimize and generate differentiated antibody therapeutic leads.

Specific Responsibilities:

• Lead protein engineering efforts to engineer antibodies and antibody fusion proteins with novel properties

• Optimize variable and constant domains of antibodies to generate therapeutic leads.

• Elucidate mechanistic understanding of targets and work to progress targets through pipeline

• Independently perform complex experiments with strong attention to detail and documentation.

• Excellent written and oral skills are necessary.

• Accomplish goals under project team time lines.


• Ph.D. in Biochemistry, Antibody engineering, chemical engineering, structural biology, or similar fields with 2-5 years post Ph.D. experience.

• Knowledgeable in engineering novel functionalities into antibodies (such as cytokines, modulating FcgRs, or FcRn interactions)

• Experience in utilizing various display technologies (yeast, phage, mammalian systems)

• Experience and knowledge of molecular biology, protein expression, purification, and characterization required.

• Immunology/Oncology experience including in-vitro cell-based assays is highly desirable

• Understanding of structure-function of proteins is a plus

• Excellent time management and organizational skills.

• Demonstrated ability to work in a multidisciplinary biologics discovery team.

Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled