Bristol Myers Squibb Associate Research Scientist in Redwood City, California
The Associate Research Scientist will join the Integrated Oncology Discovery Research team at Bristol-Myers Squibb in Redwood City, CA and aide in the advancement of early stage therapeutic targets at the intersection of tumor genetics and tumor immunobiology.
The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs from target identification/validation through IND enabling activities. The candidate will be expected to effectively collaborate with colleagues in the oncology, immunology, immuno-oncology, protein engineering/antibody development and medicinal chemistry groups. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams and key stakeholders.
· A B.S. with a minimum of 5 years of experience, or an M.S. with a minimum of 3 years of academic/industrial experience with strong scientific knowledge and research experience in cancer biology/cellular and molecular biology is required.
· Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required.
· Knowledge of preclinical drug development including knowledge of designing assays and flowcharts to identify and optimize drug candidates is required.
· Hands on experience with a wide range of in-vitro cellular and biochemical assays, including cell culture, western blotting, immunoprecipitation, ELISAs (MSD), reporter assays, siRNA/shRNA knockdown, CRISPR-mediated genome editing, qPCR, cloning, lentivirus generation and transduction is required.
· Experience with in vivo/ex vivo pharmacology, including rodent handling and common procedures including tissue processing is desired. Working knowledge of in-vivo PK, PD and efficacy studies is desirable.
· Experience in data mining through use of desktop tools/interfaces and public databases (e.g., UCSC genome Browser, CBIO, GTex, Oncoland etc) is highly desirable.
· Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required.
· Ability to mentor more junior scientists and colleagues on best practices in the laboratory would be highly valued.
· Attention to detail with excellent organizational and record keeping skills is a requirement.
· Excellent interpersonal skills with the ability to interact effectively with people, internally and externally is required.
· This position is located in Redwood City, CA. There will be less than 10% travel.
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled