Bristol Myers Squibb Research Scientist II in Princeton, New Jersey
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.
One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.
Seeking qualified (academia, biotech or pharma industry experienced) Research scientist II in the Immunoscience biology-translational discovery department to conduct in vitro and ex vivo cellular immunology assays to enhance translational immunology for portfolio projects.
The Immunoscience biology-translational discovery group at Bristol-Myers Squibb is seeking a highly motivated and collaborative scientist to join a dynamic group conducting research aimed to increase translational research for drug discovery projects covering autoimmunity and immuno-oncology. This position will support human translational research using peripheral and tissue derived primary cells in in vitro immunological assays, such as functional assays using e.g. T cells, myeloid cells, NK cells. The position will require the individual to be collaborative across other functional groups within the Discovery Research organization. Meticulous record keeping, and excellent understanding in immunology and related assays are must have requirements.
Primary human in vitro immune cell assays (e.g. T cells, B cells, myeloid cells, co-culture assays and other primary cells);
Measurements of cytokines and chemokines across different platforms (ELISA, alpha-ELISA, HTRF, MSD etc). Protein detection by single or multiplex Western blotting;
Ex vivo assays using tissues of human origins (e.g. gut, tumor samples);
Measurement of cell surface receptors and proteins by single or multicolor FACS across different platforms. Although cell sorting expertise is not a requirement, it will be highly desirable;
Expertise with analysis of biological results by interpretation and presentation of the data in a group, project teams and departmental presentation settings.
The candidate should have a Bachelor’s degree with 15 years of experience or Master's degree with 10 years of work experience (in academic, biotech or pharma industry) within the immunology area;
Extensive experience in human and murine cellular immunology assays using primary and expanded immune cells;
Experience in analysis of cytokines by single and multiplex platforms mentioned in the job description;
Experience in flow cytometry analysis of cells as well as experience in, or willingness to learn, flow cytometry based cell sorting on the platforms mentioned in the job description;
The ability to independently design and conduct experiments, including trouble-shooting outcomes and adaptively designing follow-on experiments with minimal supervision;
Proficiency in data analysis and presentation tools, as well as excellent written and oral communication skills in order to provide frequent feedback to supervisor and make presentations of progress to research teams, such as DWG;
Possess a high level of discovery research skill and critical thinking, high energy, independence, a strong desire to learn new areas, and the ability to work in a highly dynamic, transparent, research organization;
The individual should be organized and be comfortable working independently as well as in a group setting, preparing summary presentations, and participating in project meetings/discussions as required.
Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.