Bristol Myers Squibb Research Investigator - Pharmacokinetics and Quantitative Pharmacology in Princeton, New Jersey
Bristol-Myers Squibb (BMS) Department of Metabolism and Pharmacokinetics seeks a passionate scientist who wants to be a successful drug hunter in the areas of immuno-oncology drug discovery. The selected individual is expected to represent the Department on drug discovery working groups and early clinical development teams in the area of pharmacokinetics (PK)/pharmacodynamics (PD) to improve drug candidate designs, define differentiation strategies, and apply modeling and simulations to facilitate translational PK/PD efforts. The individual is also expected to take mechanistic approaches to better understand drug disposition mechanism and target pharmacology, a foundation that is crucial to our success in predicting human pharmacokinetics and efficacious dose of novel drug candidates and modalities. At BMS, we take pride in applying model-based approaches for the quantitative integration of PK/PD/efficacy/toxicity data in order to broadly impact on drug discovery and development processes. A sound understanding of PK and PD principles and hands-on experience in modeling and simulation are critical to this role. Ultimately, the selected candidate is expected to provide scientifically sound approaches and data integration for effective decision-making and enable advancement of drug candidates into clinical development.
This position will offer great opportunities on discovering multiple modalities from small molecules to biologics and integrating PK/PD modeling and evolving mechanistic understanding of Immunotherapy .
A Ph.D. in pharmacokinetics or other related discipline, with 0- to 2-year industrial experience, is required
A sound understanding of pharmacokinetic (PK) and pharmacodynamic (PD) principles and demonstrated problem-solving skills are essential to this job
Hands-on modeling experience is a requirement
In addition, strong communication skills and ability to work and collaborate in a multi-discipline team setting are required for this function
General understanding of biology is preferred
Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.