Bristol Myers Squibb Principal Scientist, Late Stage Translational Bioinformatics Oncology in Princeton, New Jersey

We are seeking a talented and motivated bioinformatics scientist to join our Late Stage Translational Bioinformatics Oncology team within the Translational Bioinformatics group at Bristol-Myers Squibb (BMS). This team is responsible for applying cutting-edge bioinformatics, statistics, and data-mining methods; working with clinical and large-scale omics data sets from BMS’s industry-leading late stage oncology/immuno-oncology (I-O) pipeline; influencing development strategies and maximizing values of BMS’s portfolio. This team of bioinformatics scientists also has the exciting opportunity to make major contributions to the scientific knowledge of cancer biology and to the improvement of treatment for cancer patients.


  • Engage late stage clinical development team, biomarker scientists,biostatisticiansand others key stakeholders todevelopand execute biomarker data analysisstrategiesfor late stage oncology clinical studies

  • Perform analysis of clinical and biomarker datasets (e.g., large-scale omics datasets includingRNASeq,exome andwholegenomesequencing, single cell sequencing) and derive clinically meaningful interpretations

  • Identify potential biomarkers for patient enrichment strategies and gain mechanistic insights of responses and resistances toI-O treatments

  • Summarize analysis results and report conclusions to BMS decision-making bodies; help communicateconclusions to regulatory agencies andthe broad scientific community

  • Evaluate and adapt latest scientific findings and methods into bioinformatics analysisplans

  • Serve as asubject-matter expertandprovidebioinformatics guidance in cross functional teams

  • Manage alliances and external collaborations


  • Ph.D. in bioinformatics, statistics, biological or physical science with10+ years of industry experience

  • Demonstrated experienceworking with clinical study data is required; familiar with late stage clinical developmentprocess

  • Deep understanding of disease biologyin immune-oncologyis a strong plus

  • Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects while conforming with rigorousrequirements ofclinical studies

  • Broad experience with data generated by one or more high-throughput molecular assays: next-generation sequencing, flow cytometry, mass spectrometry proteomics, etc.

  • Strong experienceusinghigh-level programming languagessuch as R, MATLAB, Python or Perl for complex data analysisand reproducible research practices

  • Strong problem-solving and collaboration skills,as well asrigorous and creative thinking

  • Excellentcommunication, data presentation and visualization skills

  • Capable of establishing strong working relationships across the organization

  • Strong publication record

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.