Bristol Myers Squibb Sr Research Investigator I in PRINCETON LVL, New Jersey
BMS Immuno-Oncology Small Molecule Discovery is seeking a highly motivated, creative and collaborative individual to play a key contributing role in advancing an innovative immune oncology drug discovery pipeline. Participate in pre-clinical drug discovery and development projects in immuno-oncology, primarily focusing on small molecules. Subject matter of expertise in one or two of the following areas: T cell biology, myeloid cell biology, mechanisms of immune-suppression in the tumor microenvironment, reprogramming of exhausted immune cells, tumor immunogenicity and antigen presentation. In collaboration with other team members, contribute experimentally and scientifically to target identification, validation, drug discovery and development. Employ cutting-edge in vitro and ex vivo platforms to understand the biology of IO targets in both animal as well as humanized systems. He/she will also have opportunities to support current preclinical drug development programs. The candidate will be expected to independently design, execute and analyze experiments and will be expected to present their work at both internal and external meetings. BMS is a highly matrixed organization and the successful candidate will work well within multidisciplinary teams.
· A PhD degree with 4-8 years of post-graduate research experience in immunology, tumor immunology, or a closely related field, is required. Two or more years of drug discovery experience in an industrial setting is preferred.
· Competitive candidates are expected to have a strong track record of independent and innovative research as evidenced by recent first authored publications in top tier peer-reviewed journals.
· Clear understanding of immunological mechanisms and disease relevant model systems with experience of complex immuno-phenotyping and immune cell-based functional assays
· Ideal candidates will be proficient in working with human and/or mouse primary immune cells (e.g myeloid and/or T cells), functional immune cell-based assays (e.g. T cell activation and MLR assays) and multicolor flow-cytometry.
· Highly effective communication and presentation skills, both written and oral, with ability to clearly articulate scientific hypotheses, results and conclusions to program teams and governance bodies.
· Excellent interpersonal skills and ability to work in a fast-paced and dynamic environment is essential.
We’re creating innovative medicines for patients fighting serious diseases. We’re also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.
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