Bristol Myers Squibb Research Investigator in New Brunswick, New Jersey
Scientist/engineer for conducting studies on new drug candidates to define biophysical and chemical properties using a wide variety of analytical tools, as well as to develop parenteral dosage forms and their manufacturing processes to enable clinical and commercial use.
Conduct experiments on new drug candidates and formulations to define biophysical and chemical properties using various analytical tools.
Develop parenteral dosage forms for clinical and commercial use throughout various stages of development. Generate data and knowledge for regulatory filings through planning and execution of experimental plans with minimal supervision, within project timelines.
Integrate and interpret research data and present conclusions as appropriate at various project meetings.
Conduct process development, optimization and scale-up studies; bring this knowledge to project teams to enable successful drug product technology transfer to clinical manufacturing and commercial sites.
Issue periodic reports and ensure compliance to safety rules and regulations, experimental best practices, electronic laboratory notebook, other expectations and trainings based on corporate and regulatory guidelines.
Participate on appropriate portfolio and strategy initiative teams.
Ph.D. with 0-3 years of experience or MS with 5-7 years of experience with degree in Biochemistry, Molecular Biology, Pharmaceutics, Pharmaceutical Chemistry, Bioengineering or Chemical Engineering or related disciplines
Comprehensive knowledge and understanding of protein folding and structure-activity relationship, protein/peptide chemistry, chemical and physical stability.
Hands on experience with various biophysical and analytical tools used for characterization and development.
Experience in experimental design and execution as well as independent interpretation of data generated via a wide variety of analytical techniques, available from experiments designed by self or others.
Knowledge of fundamental principles of pharmaceutical science essential for the development of injectable dosage forms of small molecule, protein and peptide therapeutics.
Basic understanding of process development (lyophilized or ready-to-use) and scale-up of injectable dosage forms to clinical or commercial manufacturing sites is preferred.
Excellent team player with good interpersonal, written, verbal communication skills.
Hands on computer skills and knowledge of statistics.
Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.