Bristol Myers Squibb Senior Research Scientist: Vivo Pharmacology in Princeton, New Jersey
Title: Senior Research Scientist: Vivo Pharmacology
Job Number: 1703691
BMS Immuno-Oncology Small Molecule Discovery is seeking a highly motivated, creative and collaborative in vivo pharmacologist to play a key contributing role in advancing an innovative immune oncology drug discovery pipeline. Responsibilities for this senior research scientist position include designing, and executing a wide range of in vivo and ex vivo studies aiming to understand the pharmacological properties and mechanism of action of various therapeutic agents. The ideal candidate possess extensive hands-on experience with standard tumor and/or metastatic models, and a good understanding of cellular immunity and host responses to cancer. Ability to develop new mouse models of tumorigenesis and experience with ex vivo functional assays interrogating the immune system are required. The qualified candidate possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs from target identification/validation through IND enabling activities. Maintain meticulous record keeping, write reports in support of program and regulatory activities, and present at internal meetings.
Bachelor’s degree and a minimum of 13 years (or Master's degree plus 10 years) of relevant experience in in vivo pharmacology with an emphasis in Immuno-oncology and the tumor microenvironment preferably within the Pharmaceutical/Biotechnology sector;
Experienced on ex-vivo studies, including phenotypic and functional analysis of tumor infiltrating cells. Hands on experience with methods in cellular and molecular immuno-oncology;
Substantial experienced in using multi-parametric flow cytometry for the staining and analysis of immune cells using multiple platforms for data acquisition. Experienced in, or willingness to learn, flow cytometry based cell sorting;
Write animal protocols, help secure protocol authorization and maintain compliance;
Demonstrated independence in experimental design, execution, and data analysis;
Detail-oriented with excellent organizational and record-keeping skills;
Comfortable working independently as well as in a group setting;
Excellent communication skills with ability to effectively communicate both oral and written scientific results to peers, supervisor and department teams;
Ability to mentor colleagues.
Bristol-Myers Squibb is an equal opportunity employer - Minorities/Females/Protected Veterans/Disabled
Job: Biology - Discovery